Navigation
| Move Between Regions | Tab |
| Move Within Regions | Up and Down Arrow Keys |
Shortcuts for Sending Mail
| Create a new message | Ctrl + N OR Ctrl + Shift + M |
| Reply to a message | Ctrl + R |
| Reply all to a message | Ctrl + Shift + R |
| Forward a message | Ctrl + F |
| Send message | Ctrl + Enter |
| Add an attachment | Alt + I |
Managing Your Inbox
| Delete a message | Ctrl + D OR Delete |
| Archive a message | Backspace |
| Mark as read | Ctrl + Q |
| Mark as unread | Ctrl + U |
| Toggle important status | Ctrl + Shift + G |
| Search | Ctrl + E |
Accessibility
The Windows 10 Mail app has had some accessibility issues in the past. How the app functions for screen reader users seems to be improving, but it certainly isn’t at 100 percent accessibility and usability as of yet. Below are a couple of articles and resources from Microsoft on accessibility and Windows 10 Mail.
Article from Microsoft Accessibility Blog on the accessibility of Windows 10 Mail
Guide from Microsoft Office Support on using a screen reader with Windows 10 Mail
Guide from Microsoft Office Support on reading emails with a screen reader in Windows 10 Mail
Vermont DBVI Training 